| Identification | Back Directory | [Name]
2-(4,5-DIHYDROIMIDAZOL-2-YL)ISOQUINOLINE HYDROCHLORIDE | [CAS]
1186195-56-1 | [Synonyms]
BU-226 HCL
BU 226 HYDROCHLORIDE
3-(4,5-dihydro-1H-imidazol-2-yl)isoquinoline
2-(4,5-DIHYDROIMIDAZOL-2-YL)ISOQUINOLINE HYDROCHLORIDE
Inhibitor,BU-226,antidepressant,inhibit,BU 226 hydrochloride,Imidazoline Receptor,BU 226,BU226 | [Molecular Formula]
C12H14ClN3 | [MDL Number]
MFCD09753378 | [MOL File]
1186195-56-1.mol | [Molecular Weight]
235.713 |
| Hazard Information | Back Directory | [Uses]
BU226 hydrochloride is a selective imidazoline 2 (I2) receptors ligand with an Ki of 1.4 nM for I2 and an IC50 of 534.5 nM for I1. BU226 hydrochloride can be used for researching antidepressant[1]. | [Biological Activity]
A high affinity ligand for I 2 imidazoline sites (K i = 2.7 nM) with very high selectivity (> 2000-fold) over α 2 -adrenoceptors (K i = 6700 nM). | [References]
[1] Hudson AL, et al. Novel selective compounds for the investigation of imidazoline receptors. Ann N Y Acad Sci. 1999 Jun 21;881:81-91. DOI:10.1111/j.1749-6632.1999.tb09344.x |
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
InvivoChem
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| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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