ChemicalBook--->CAS DataBase List--->118719-16-7

118719-16-7

118719-16-7 Structure

118719-16-7 Structure
IdentificationBack Directory
[Name]

N'-[(1E)-(5-bromo-2-hydroxyphenyl)methylidene]-4-methylbenzene-1-sulfonohydrazide
[CAS]

118719-16-7
[Synonyms]

dCeMM1
N'-(5-bromo-2-hydroxybenzylidene)-4-methylbenzenesulfonohydrazide
N'-[(1E)-(5-bromo-2-hydroxyphenyl)methylidene]-4-methylbenzene-1-sulfonohydrazide
[EINECS(EC#)]

657-003-0
[Molecular Formula]

C14H13BrN2O3S
[MDL Number]

MFCD00415337
[MOL File]

118719-16-7.mol
[Molecular Weight]

369.234
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H335-H319
[Precautionary statements ]

P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Hazard InformationBack Directory
[Uses]

dCeMM1 is a RBM39 glue degrader. dCeMM1 shows functions by re-directing the activity of the CRL4DCAF15 ligase. dCeMM1 decreases the expression of RBM39 levels in WT KBM7 cells[1].
[References]

[1] Mayor-Ruiz C, et al. Rational discovery of molecular glue degraders via scalable chemical profiling. Nat Chem Biol. 2020 Nov;16(11):1199-1207.
Spectrum DetailBack Directory
[Spectrum Detail]

N'-[(1E)-(5-bromo-2-hydroxyphenyl)methylidene]-4-methylbenzene-1-sulfonohydrazide(118719-16-7)1HNMR
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