| Identification | Back Directory | [Name]
PF-04856881 | [CAS]
1187653-56-0 | [Synonyms]
PF4856881
PF-4856881
PF 4856881
PF04856881
PF-04856881
PF 04856881
ADL-5747 (HCl)
ADL5747 (HCl),ADL 5747 (HCl) | [Molecular Formula]
C24H29ClN2O3 | [MOL File]
1187653-56-0.mol | [Molecular Weight]
428.96 |
| Hazard Information | Back Directory | [Uses]
ADL-5747 hydrochloride is a selective and orally active agonist of the δ-opioid receptor (DOR). By binding to the δ-opioid receptors, ADL-5747 hydrochloride activates these receptors, thereby playing a role in pain management pathways. ADL-5747 hydrochloride can be used for research into pain management mechanisms[1]. | [References]
[1] Le Bourdonnec B, et al. Spirocyclic delta opioid receptor agonists for the treatment of pain: discovery of N, N-diethyl-3-hydroxy-4-(spiro [chromene-2, 4′-piperidine]-4-yl) benzamide (ADL5747)[J]. Journal of medicinal chemistry, 2009, 52(18): 5685-5702. DOI:10.1021/jm900773n |
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