| Identification | Back Directory | [Name]
Isolan powder(content2%-20%) | [CAS]
119-38-0 | [Synonyms]
Saolan
G-23611
ISOLANE
IsolanR
ENT-19060
Primin powder
Primin emulsion
RNNBHZYEKNHLKT-UHFFFAOYSA-N
Isolan powder(content2%-20%)
Isolan emulsion(content0.5%-20%)
1-isopropyl-3-methylpyrazol-5-yl dimethylcarbamate
Isopropylmethylpyrazolyl dimethylcarbamate: (Isolan)
DIMETHYLCARBAMICACID-1-ISOPROPYL-3-METHYLPYRAZOLE-5-YL
1-isopropyl-3-methylpyrazol-5-yl dimethylcarbamate isolan
(5-methyl-2-propan-2-ylpyrazol-3-yl) N,N-dimethylcarbamate
(5-methyl-2-propan-2-yl-pyrazol-3-yl) N,N-dimethylcarbamate
N,N-Dimethylcarbamic acid 1-isopropyl-3-methyl-1H-pyrazol-5-yl
N,N-dimethylcarbamic acid (2-isopropyl-5-methyl-pyrazol-3-yl) ester
N,N-Dimethylcarbamic acid 1-isopropyl-3-methyl-1H-pyrazol-5-yl ester
Carbamicacid,dimethyl-,3-methyl-1-(1-methylethyl)-1H-pyrazol-5-ylester
Carbamic acid, N,N-dimethyl-, 3-methyl-1-(1-methylethyl)-1H-pyrazol-5-yl ester | [EINECS(EC#)]
204-318-2 | [Molecular Formula]
C10H17N3O2 | [MOL File]
119-38-0.mol | [Molecular Weight]
211.261 |
| Chemical Properties | Back Directory | [Appearance]
Liquid. Miscible with water. | [Boiling point ]
bp0.7 103°; bp2.5 117.5-118° | [density ]
1.07 | [refractive index ]
1.4830 (estimate) | [Henry's Law Constant]
4.9×103 mol/(m3Pa) at 25℃, HSDB (2015) | [InChI]
1S/C10H17N3O2/c1-7(2)13-9(6-8(3)11-13)15-10(14)12(4)5/h6-7H,1-5H3 | [SMILES]
CC(C)N1C(OC(N(C)C)=O)=CC(C)=N1 | [CAS DataBase Reference]
119-38-0 | [EPA Substance Registry System]
Isolane (119-38-0) |
| Hazard Information | Back Directory | [Chemical Properties]
Liquid. Miscible with water. | [Uses]
Insecticide. | [General Description]
Colorless liquid. Used as a systemic aphicide in Europe, insecticide. Currently of little commercial interest. Not registered as a pesticide in the U.S. | [Reactivity Profile]
Isolan powder(content2%-20%) is a carbamate ester. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates. | [Health Hazard]
Isolan powder(content2%-20%) is classified as extremely toxic. Probable oral lethal dose in humans is 5-50 mg/kg or between 7 drops and 1 teaspoonful for a 150-lb. person. A cholinesterase inhibitor; although it is not an organic phosphate, it resembles that group in action. | [Fire Hazard]
When heated to decomposition, Isolan powder(content2%-20%) emits toxic fumes of nitrogen oxides. | [Hazard]
Cholinesterase inhibitor. | [Production Methods]
The commercial production of isolan involves the synthesis of the pyrazole ring followed by carbamoylation using dimethylcarbamoyl chloride or a similar reagent. The process typically includes condensation of isopropylhydrazine with methyl ethyl ketone to form the substituted pyrazole, which is then esterified with dimethylcarbamic acid derivatives. The final product is purified through distillation or crystallisation. | [Mechanism of action]
Systemic. Acetylcholinesterase (AchE) inhibitor. | [Pesticide Type]
Insecticide |
| Safety Data | Back Directory | [Hazard Codes ]
T+ | [Risk Statements ]
27/28 | [Safety Statements ]
28-36/37/39-45 | [RIDADR ]
2992 | [WGK Germany ]
WGK 3 | [HazardClass ]
6.1(a) | [PackingGroup ]
I | [Storage Class]
6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials | [Hazard Classifications]
Acute Tox. 1 Dermal
Acute Tox. 2 Oral | [Safety Profile]
Poison by ingestion,
skin contact, and intraperitoneal routes.
Questionable carcinogen with experimental
tumorigenic data. Mutation data reported.
An insecticide. When heated to
decomposition it emits toxic fumes of NOx.
See also CARBAMATES | [Hazardous Substances Data]
119-38-0(Hazardous Substances Data) | [Toxicity]
LD50 in male, female rats (mg/kg): 23, 13 orally; 5.6, 6.2 dermally (Gaines, 1969) |
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