| Identification | Back Directory | [Name]
LY 278584 | [CAS]
119193-37-2 | [Synonyms]
LY 278584
CID 5311254
LY-278584; LY 278584
1H-Indazole-3-carboxamide, 1-methyl-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-
1-METHYL-N-[(1R,5S)-8-METHYL-8-AZABICYCLO[3.2.1]OCTAN-3-YL]INDAZOLE-3-CARBOXAMIDE | [Molecular Formula]
C17H22N4O | [MDL Number]
MFCD00213570 | [MOL File]
119193-37-2.mol | [Molecular Weight]
298.38 |
| Hazard Information | Back Directory | [Uses]
LY 278584 is a potent, highly selective 5-HT3 receptor antagonist with a Ki of 1.62 nM. LY 278584 has no activity on 5-HT1A, 5-HT1B, 5-HT1C, 5-HT1D, or 5-HT2 receptors[1]. | [Definition]
ChEBI: 1-methyl-N-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)-3-indazolecarboxamide is an aromatic amide and a member of indazoles. | [IC 50]
5-HT3 Receptor: 1.62 nM (Ki) | [References]
[1] D W Robertson, et al. Synthesis and biochemical evaluation of tritium-labeled 1-methyl-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-1H-indazole-3-carboxa mide, a useful radioligand for 5HT3 receptors. J Med Chem. 1990 Dec;33(12):3176-81. DOI:10.1021/jm00174a013 |
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Alomone Labs
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4008-168-068 13121892008 |
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www.alomone.com |
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BOC Sciences
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16314854226 |
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www.bocsci.com |
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