| Identification | Back Directory | [Name]
HP 184 | [CAS]
119229-65-1 | [Synonyms]
HP 184
Nerispirdine
1H-Indol-1-amine, N-(3-fluoro-4-pyridinyl)-3-methyl-N-propyl- | [Molecular Formula]
C17H18FN3 | [MOL File]
119229-65-1.mol | [Molecular Weight]
283.34 |
| Hazard Information | Back Directory | [Uses]
Nerispirdine is an ion channel inhibitor with IC50s of 3.6, 3.7 and 11.9 μM against K(v)1.1, K(v)1.2 and voltage-dependent Na(+) channel, respectively. Nerispirdine is a 4-aminopyridine (4-AP, HY-B0604) derivative and can be utilized in research on neurological disorders[1]. | [References]
[1] Smith C, et al. In Vitro electrophysiological activity of nerispirdine, a novel 4-aminopyridine derivative. Clin Exp Pharmacol Physiol. 2009 Nov;36(11):1104-9. DOI:10.1111/j.1440-1681.2009.05200.x |
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