| Identification | Back Directory | [Name]
Meribendan | [CAS]
119322-27-9 | [Synonyms]
Meribendan
3(2H)-Pyridazinone, 4,5-dihydro-5-methyl-6-[2-(1H-pyrazol-3-yl)-1H-benzimidazol-6-yl]- | [Molecular Formula]
C15H14N6O | [MDL Number]
MFCD00867142 | [MOL File]
119322-27-9.mol | [Molecular Weight]
294.31 |
| Hazard Information | Back Directory | [Uses]
Meribendan is a phosphodiesterase (PDE)-III inhibitor[1][2]. | [IC 50]
PDE Ⅲ | [References]
[1] Jonas R, et al. Synthesis and biological activities of meribendan and related heterocyclic benzimidazolo-pyridazinones. Cheminform, 1993, 24(30).
[2] De Mey C, et al. Differentiation of inodilatory responses by non-invasive measures of cardiovascular performance in healthy man. Int J Clin Pharmacol Ther. 1996 Dec;34(12):525-32. PMID:8996846 |
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