ChemicalBook--->CAS DataBase List--->1194508-25-2

1194508-25-2

1194508-25-2 Structure

1194508-25-2 Structure
IdentificationBack Directory
[Name]

Edivoxetine
[CAS]

1194508-25-2
[Synonyms]

LY 2216684
Edivoxetine
(R)-2-(5-fluoro-2-methoxyphenyl)-1-((S)-morpholin-2-yl)-1-(tetrahydro-2H-pyran-4-yl)ethan-1-ol
2-Morpholinemethanol, α-[(5-fluoro-2-methoxyphenyl)methyl]-α-(tetrahydro-2H-pyran-4-yl)-, (αR,2S)-
[Molecular Formula]

C18H26FNO4
[MDL Number]

MFCD27987928
[MOL File]

1194508-25-2.mol
[Molecular Weight]

339.41
Chemical PropertiesBack Directory
[Boiling point ]

484.3±40.0 °C(Predicted)
[density ]

1.198±0.06 g/cm3(Predicted)
[pka]

13.62±0.29(Predicted)
Hazard InformationBack Directory
[Uses]

Edivoxetine is a selective and potent norepinephrine reuptake inhibitor (NERI) being used in depressive disorder or attention-deficit/hyperactivity disorder.
[References]

[1] Jin L, Xu W, Krefetz D, et al. Clinical outcomes from an open-label study of edivoxetine use in pediatric patients with attention-deficit/hyperactivity disorder. J Child Adolesc Psychopharmacol. 2013;23(3):200-207. DOI:10.1089/cap.2012.0016
[2] Kielbasa W, Tesfaye E, Luffer-Atlas D, Mitchell MI, Turik MA. The effect of hepatic or renal impairment on the pharmacokinetics of edivoxetine, a selective norepinephrine transporter reuptake inhibitor. Eur J Clin Pharmacol. 2013;69(12):2011-2019. DOI:10.1007/s00228-013-1572-y
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