ChemicalBook--->CAS DataBase List--->119474-55-4

119474-55-4

119474-55-4 Structure

119474-55-4 Structure
IdentificationBack Directory
[Name]

KB 5246
[CAS]

119474-55-4
[Synonyms]

KB 5246
[Molecular Formula]

C18H17ClFN3O4S
[MDL Number]

MFCD00877050
[MOL File]

119474-55-4.mol
[Molecular Weight]

425.86
Chemical PropertiesBack Directory
[Melting point ]

287 °C (decomp)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
Hazard InformationBack Directory
[Uses]

KB-5246 is a tetracyclic quinolone and displays antibacterial activities.
[in vivo]

The 50% effective dose values of KB-5246 against S. pneumoniae 2132 infections are 50.5 mg/kg of body weight. The activities of KB-5246 against S. aureus Smith, P. aeruginosa GN11189, and Serratia marcescens GN7577 infections are comparable to those of ofloxacin and greater than those of norfloxacin[1].

[IC 50]

Quinolone
[References]

[1] Kotera Y, et al. In vitro and in vivo antibacterial activities of KB-5246, a new tetracyclic quinolone. Antimicrob Agents Chemother. 1989 Nov;33(11):1896-900. DOI:10.1128/AAC.33.11.1896
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