| Identification | Back Directory | [Name]
5-Pyrimidinecarboxamide, 2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[[4-(2H-1,2,3-triazol-2-yl)phenyl]amino]-, rel- | [CAS]
1194954-83-0 | [Synonyms]
5-Pyrimidinecarboxamide, 2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[[4-(2H-1,2,3-triazol-2-yl)phenyl]amino]-, rel- | [Molecular Formula]
C19H23N9O | [MOL File]
1194954-83-0.mol | [Molecular Weight]
393.45 |
| Hazard Information | Back Directory | [Description]
BIIB-057 is a selective Syk inhibitor. | [Uses]
Syk-IN-11 (BIIB-057) is a selective Syk inhibitor with an IC50 Of 13 nM. Syk-IN-11 can be used in the study of arthritis and chronic lymphocytic leukemia[1]. | [References]
[1] Lucas MC, et al. Small-molecule inhibitors of spleen tyrosine kinase as therapeutic agents for immune disorders: will promise meet expectations? Future Med Chem. 2014;6(16):1811-27. DOI:10.4155/fmc.14.126 |
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