| Hazard Information | Back Directory | [Description]
TIBI is a potent ATP-competitive dual inhibitor of Rio1 and CK2. | [Uses]
TIBI is a potent and ATP-competitive inhibitor of Rio1 (IC50: 0.09 μM, Ki: 0.05 μM). TIBI enhances the thermostability of the enzyme Rio1[1]. | [References]
[1] Kubiński K, et al. Benzimidazole inhibitors of protein kinase CK2 potently inhibit the activity of atypical protein kinase Rio1. Mol Cell Biochem. 2017 Feb;426(1-2):195-203. DOI:10.1007/s11010-016-2892-x |
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