| Identification | Back Directory | [Name]
N- [1- [(1R, 3S, 4S, 6R, 7S) - 4- [[Bis(4- Methoxyphenyl) - Phenylmethoxy] Methyl] - 7- [2- Cyanoeth | [CAS]
1197033-17-2 | [Synonyms]
S-cEt-C phosphoramidite
5'-O-DMTr-cEt-BNA-N-Bz-Me-Cytidine-CEP
5'-ODMT cEt N-Bz 5-Me C Phosphoramidite
N- [1- [(1R, 3S, 4S, 6R, 7S) - 4- [[Bis(4- Methoxyphenyl) - Phenylmethoxy] Methyl] - 7- [2- Cyanoeth
Benzamide, N-[1-[2,5-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-6-deoxy-α-L-mannofuranosyl]-1,2-dihydro-5-methyl-2-oxo-4-pyrimidinyl]- | [Molecular Formula]
C49H56N5O9P | [MOL File]
1197033-17-2.mol | [Molecular Weight]
889.97 |
| Hazard Information | Back Directory | [Uses]
5'-ODMT cEt N-Bzm5 C Phosphoramidite Amidite is a potent nucleic acid analog. 5'-ODMT cEt N-Bzm5 C Phosphoramidite Amidite blongs to modified antisense oligonucleotide. 5'-ODMT cEt N-Bzm5 C Phosphoramidite Amidite allows the formation of a specific conformation of the furanose ring of the oligonucleotide through the introduction of a cEt modification, enhancing the ability to hybridize to complementary RNA. 5'-ODMT cEt N-Bzm5 C Phosphoramidite Amidite is mainly used in the research of regulation of gene expression related to metabolic diseases, cardiovascular diseases, cancers and the development of antisense compounds[1][2]. | [References]
[1] Yu J, et al. Synthesis and antisense properties of 2'-O-(2S-methoxypropyl)-RNA-modified gapmer antisense oligonucleotides. ChemMedChem. 2014 Sep;9(9):2040-4. DOI:10.1002/cmdc.201402099
[2] Seth P P, et al. Synthesis and biophysical evaluation of 2′, 4′-constrained 2′ O-methoxyethyl and 2′, 4′-constrained 2′ O-ethyl nucleic acid analogues. The Journal of organic chemistry, 2010, 75(5): 1569-1581. |
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https://www.newcanbio.com/ |
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