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1197333-54-2

1197333-54-2 Structure

1197333-54-2 Structure
IdentificationBack Directory
[Name]

3-(1-METHYLPIPERIDIN-4-YL)-1H-INDOL-5-OL MALEATE
[CAS]

1197333-54-2
[Synonyms]

BRL 54443 MALEATE
BRL 54443 maleate salt
3-(1-METHYLPIPERIDIN-4-YL)-1H-INDOL-5-OL MALEATE
3-(1-Methylpiperidin-4-yl)-1H-indol-5-ol maleate salt
1H-Indol-5-ol, 3-(1-methyl-4-piperidinyl)-, (2Z)-2-butenedioate (1:1)
[Molecular Formula]

C18H22N2O5
[MDL Number]

MFCD01860866
[MOL File]

1197333-54-2.mol
[Molecular Weight]

346.38
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

H2O: 50 mg/mL
[form ]

solid
[color ]

white
[Water Solubility ]

H2O: 50mg/mL
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P264-P271-P280-P302+P352-P305+P351+P338
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-36
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

BRL 54443 Maleate Salt can be used in pharmacological activity and biological study of forskolin-free cAMP assay for Gi-coupled receptors.
[Biological Activity]

Potent 5-HT1E/1F serotonin receptor agonist.
[in vivo]

Reduction of flinching was considered as antinociception. Ipsilateral, but not contralateral, peripheral administration of BRL54443 (5-HT(1E/1F); 3-300 microg/paw) significantly reduced formalin-induced flinching in rats[3].

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