| Identification | Back Directory | [Name]
2-chloro-4-iodo-5-methylpyridine | [CAS]
1197957-18-8 | [Synonyms]
2-chloro-4-iodo-5-methylpyridine
Pyridine, 2-chloro-4-iodo-5-methyl- | [Molecular Formula]
C6H5ClIN | [MDL Number]
MFCD16610529 | [MOL File]
1197957-18-8.mol | [Molecular Weight]
253.47 |
| Chemical Properties | Back Directory | [Boiling point ]
277℃ | [density ]
1.906 | [Fp ]
122℃ | [storage temp. ]
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | [form ]
crystalline powder | [pka]
0.37±0.10(Predicted) | [color ]
cream/faint orange | [InChI]
InChI=1S/C6H5ClIN/c1-4-3-9-6(7)2-5(4)8/h2-3H,1H3 | [InChIKey]
ZWCNVOMJDJPZHE-UHFFFAOYSA-N | [SMILES]
C1(C(I)=CC(Cl)=NC=1)C |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302 | [Precautionary statements ]
P280-P305+P351+P338 | [Hazard Codes ]
Xn | [Risk Statements ]
22 | [HazardClass ]
IRRITANT | [HS Code ]
2933399990 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral |
| Hazard Information | Back Directory | [Chemical Properties]
The chemical structure of 2-chloro-4-iodo-5-methylpyridine contains iodine atoms and chlorine atoms, which have rich chemical transformation properties. Firstly, the iodine atom in the structure of the substance can have cross-coupling reaction with imidazole compounds under the catalytic effect of metallic copper, and it can also have coupling reaction with arylboronic acid substances and organic zinc reagents under the catalytic effect of metallic palladium. It is worth noting that the pyridine unit in 2-chloro-4-iodo-5-methylpyridine is more sensitive to oxidants, and is easily oxidized to the corresponding nitrogen oxides when exposed to oxidants. |
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