| Identification | Back Directory | [Name]
2(S)-Amino-4-azido-butanoic Acid | [CAS]
120042-14-0 | [Synonyms]
Ccris 3366
H-g-azido-Abu-OH
H-D-Dab(N3)-OH·HCl
4-Azido-hoMoalanine
H-gamma-azido-Abu-OH
AzidohoMoanaline (AHA)
2(S)-Amino-4-azido-butanoic Acid
(S)-2-Amino-4-azidobutanoic acid
(2S)-2-Amino-4-azido-butanoic Acid
D-2-amino-4-azidobutanoic acid hydrochloride
H-Dab(N2)-OH, L-g-azidohoMoalanine, H-g-Aha-OH
Nγ-Azido-D-2,4-diaminobutyric acid hydrochloride≥ 98% (HPLC) | [Molecular Formula]
C4H8N4O2 | [MDL Number]
MFCD18382041 | [MOL File]
120042-14-0.mol | [Molecular Weight]
144.13 |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Solid | [Uses]
A novel mutagenic amino acid | [Description]
L-azidohomoalaine provides a fast, sensitive, non-toxic and non-radioactive alternative to the traditional radioactive technique, 35S-methionine for the detection of nascent protein. L-azidohomoalaine is an amino acid analog that contains a small modification and its azido moiety can be fed to cultured cells and incorporated into proteins during active protein synthesis. | [Synthesis]
A concise and highly efficient synthetic route to l-azidohomoalanine (l-Aha) and its homologues is presented here. Starting from inexpensive N-Boc-O-Bn-l-aspartic acid, gram quantities of l-Aha hydrochloride can be prepared with high purity. The reactions can be completed within 1 week and the products can be incorporated into proteins using l-methionine auxotrophs.
| [IC 50]
Alkyl-Chain | [References]
[1] STEFANIE ROTH Neil R T William C Drewe. A concise and scalable route to L-azidohomoalanine[J]. Nature Protocols, 2010, 5 12: 1967-1973. DOI:10.1038/nprot.2010.164. |
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BOC Sciences
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1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
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021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
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