| Identification | Back Directory | [Name]
Gadoteridol | [CAS]
120066-54-8 | [Synonyms]
0))-
prohance
SQ 32692
gd-hp-do3a
gadotridol
Gadoteridol
ICG-Hydrazide
ICG-Maleimide
disulfo-ICG-NHS
gadolinium-hp-do3a
GADOTERIDOL (500 MG)
Gadoteridol USP/EP/BP
diSulfo-ICG Maleimide
diSulfo-ICG Hydrazide
triSulfo-Cy5.5 hydrazide
triSulfo-Cy5.5 Maleimide
1-Chloro-3-dodecylbenzene
Anti-6,6'-disulfo LacNAc Monoclonal Antibody (L4L4-8)
2,4-Dibromo-17,17-ethylenedioxy-1,3,5(10)-estratriene-3-ol
to(3-)-n(sup1),n(sup4),n(sup7),n(sup10),o(sup1),o(sup4),o(sup7),o(sup1
Gadolinium 10-(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecan-1,4,7-triacetate
gadolinium,(10-(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triaceta | [EINECS(EC#)]
1533716-785-6 | [Molecular Formula]
C17H29GdN4O7 | [MDL Number]
MFCD20037423 | [MOL File]
120066-54-8.mol | [Molecular Weight]
558.68 |
| Chemical Properties | Back Directory | [Melting point ]
188-193 °C | [storage temp. ]
Store at -20°C | [solubility ]
PBS (pH 7.2): 10 mg/ml | [form ]
A solid | [color ]
White to off-white | [Appearance]
dark green powder | [InChI]
InChI=1S/C17H31N4O7.Gd/c1-14(22)10-18-2-4-19(11-15(23)24)6-8-21(13-17(27)28)9-7-20(5-3-18)12-16(25)26;/h14H,2-13H2,1H3,(H,23,24)(H,25,26)(H,27,28);/q-1;+4/p-3 | [InChIKey]
JOJFJDKAWWEUPD-UHFFFAOYSA-K | [SMILES]
CC1CN23CCN45CCN67CCN8(CC2)CC(=O)[O-][Gd+3]3486([O-]C(=O)C5)([O-]C(=O)C7)O1 |
| Hazard Information | Back Directory | [Description]
Indocyanine Green (ICG, IC Green, Foxgreen) is a negatively charged tricarbocyanine dye widely used for imaging and flow cytometry due to its low toxicity and near-infrared fluorescence emission.
ICG has an absorption maximum at 787 nm with slight absorption in the visible range and a fluorescence emission maximum at 819 nm. The minimal light scattering and low autofluorescence in this spectral range result in a significantly reduced background and improved signal-to-noise ratios, thereby enhancing detection sensitivity.
ICG maleimide is a thiol-reactive dye for labeling of protein SH groups, and it can be used to attach ICG fluorophore to proteins and peptides containing cysteine residues, as well as to other thiolated molecules (such as thiol-containing oligonucleotides). Cystines should be reduced with TCEP (tris-carboxyethylphosphine) or with another appropriate reductant prior to the labeling. | [Uses]
Diagnostic aid (paramagnetic). | [Definition]
ChEBI: A non-ionic gadolinium chelate having a macrocyclic tetraamine framework. It is used as a paramagnetic contrast agent in magnetic resonance imaging (MRI). | [Brand name]
Prohance (Bracco). | [General Description]
Gadoteridol is a nonionicclear, colorless to slightly yellow, gadolinium-based contrastagent indicated to visualize lesions with abnormal vascularityin the CNS, head, and neck. It is a hypertonic solutionwith an osmolality of 2.2 times that of plasma. Clinical enhancementof images occurs primarily when using T1-weighted sequences. | [Abs/Em Maxima]
787/819 nm | [Fluoresene quantum yield]
0.09 | [Extinction Coefficient]
232000 |
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