| Identification | Back Directory | [Name]
Ixazomib Impurity 1 | [CAS]
1201903-02-7 | [Synonyms]
Ixazomib Impurity 1
2,5-dichloro-N-(2-(((R)-3-methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-2-oxoethyl)benzamide
2,5-Dichloro-N-[2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxoethyl]-benzamide
Benzamide, 2,5-dichloro-N-[2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxoethyl]- | [Molecular Formula]
C24H33BCl2N2O4 | [MOL File]
1201903-02-7.mol | [Molecular Weight]
495.25 |
| Chemical Properties | Back Directory | [Boiling point ]
602.0±55.0 °C(Predicted) | [density ]
1.25±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
Dichloromethane; Chloroform; Methanol; Ethyl Acetate; DMSO; | [form ]
Solid | [pka]
12.10±0.46(Predicted) | [color ]
White | [InChIKey]
CGUIBVMGUKXODV-OPKBTAHXSA-N | [SMILES]
C(NCC(N[C@H](B1O[C@@]2(C)[C@@]3([H])C[C@@]([H])(C[C@@]2([H])O1)C3(C)C)CC(C)C)=O)(=O)C1=CC(Cl)=CC=C1Cl |
| Hazard Information | Back Directory | [Uses]
2,5-Dichloro-N-[2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxoethyl]-benzamide is an intermediate used in the synthesis of Ixazomib (I942000), which is a proteasome inhibitor that acts by preventing cell growth in solid tumours. It is an anticancer agent that is used to treat patients with multiple myeloma and is potentially neurotoxic. |
|
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
|