| Hazard Information | Back Directory | [Description]
JCP-170 is an inhibitor of ABHD6 that works in a dose-dependent manner. | [Uses]
JCP-170, a substituted chloroisocoumarin, is an ABHD6 inhibitor. JCP-170 robustly and reproducibly inhibits metastatic seeding of the murine cell line 0688M and both human pancreatic ductal adenocarcinoma (PDAC) cell lines[1]. | [References]
[1] Grüner BM, et al. An in vivo multiplexed small-molecule screening platform. Nat Methods. 2016 Oct;13(10):883-889. DOI:10.1038/nmeth.3992 |
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