| Identification | Back Directory | [Name]
4H-1,2,4-Triazole, 3-(2-chloro-4-fluorophenyl)-4-methyl-5-[1-methyl-1-(2,4,6-trifluorophenoxy)ethyl]- | [CAS]
1203956-47-1 | [Synonyms]
-HSD1-IN-1
11β-HSD1-IN-1
11β-HSD1-IN-1
11β-HSD-1-IN-1,11βHSD1IN1,11β HSD1 IN 1
4H-1,2,4-Triazole, 3-(2-chloro-4-fluorophenyl)-4-methyl-5-[1-methyl-1-(2,4,6-trifluorophenoxy)ethyl]- | [Molecular Formula]
C18H14ClF4N3O | [MDL Number]
MFCD31544428 | [MOL File]
1203956-47-1.mol | [Molecular Weight]
399.77 |
| Chemical Properties | Back Directory | [Boiling point ]
507.3±60.0 °C(Predicted) | [density ]
1.39±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
1.38±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1), with an IC50 of 52 nM, and used for the treatment of pain. | [Uses]
11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1), with an IC50 of 52 nM, and used for the treatment of pain. | [References]
[1]. THERAPEUTIC AGENT FOR PAIN. WO2012033070A1 |
|
|