ChemicalBook--->CAS DataBase List--->1205538-83-5

1205538-83-5

1205538-83-5 Structure

1205538-83-5 Structure
IdentificationBack Directory
[Name]

CalpinactaM
[CAS]

1205538-83-5
[Synonyms]

FKI-4905
CalpinactaM
D-Alloisoleucinamide, D-phenylalanyl-L-leucyl-L-histidyl-D-α-glutamyl-N-[(3S)-hexahydro-2-oxo-1H-azepin-3-yl]-
D-Phenylalanyl-L-leucyl-L-histidyl-D-alpha-glutamyl-N-[(3S)-hexahydro-2-oxo-1H-azepin-3-yl]-D-alloisoleucinamide
[Molecular Formula]

C38H57N9O8
[MDL Number]

MFCD28899524
[MOL File]

1205538-83-5.mol
[Molecular Weight]

767.915
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: soluble
[form ]

A solid
[color ]

Off-white
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302+H312+H332
[Precautionary statements ]

P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P321-P330-P362+P364-P501
Hazard InformationBack Directory
[Description]

Calpinactam is a fungal metabolite with antimycobacterial activity. It is active against M. smegmatis.
[Uses]

Calpinactam (FKI-4905), a fungal metabolite, is a new anti-mycobacterial agent.Calpinactam is active only against Mycobacteria among various microorganisms, including Gram-positive and Gram-negative bacteria, fungi and yeasts. Calpinactam inhibits the growth of Mycobacterium smegmatis and Mycobacterium tuberculosis with MIC values of 0.78 and 12.5 μg/ml, respectively[1].
[IC 50]

Fungal Metabolite
[storage]

+4°C
[References]

[1] Nobuhiro Koyama, et al.Calpinactam, a new anti-mycobacterial agent, produced by Mortierella alpina FKI-4905. J Antibiot (Tokyo). 2010 Apr;63(4):183-6. DOI:10.1038/ja.2010.14
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