| Identification | Back Directory | [Name]
4-Phosphonophenylglycine | [CAS]
120667-15-4 | [Synonyms]
(RS)-PPG
4-Phosphonophenylglycine
(RS)-PHOSPHONOPHENYLGLYCINE
(RS)-4-PHOSPHONOPHENYLGLYCINE
2-(4-phosphonoanilino)aceticaci
4-Phosphonophenylglycine USP/EP/BP
Benzeneacetic acid, α-amino-4-phosphono- | [Molecular Formula]
C8H10NO5P | [MDL Number]
MFCD02262122 | [MOL File]
120667-15-4.mol | [Molecular Weight]
231.14 |
| Chemical Properties | Back Directory | [Boiling point ]
515.5±60.0 °C(Predicted) | [density ]
1.61±0.1 g/cm3(Predicted) | [storage temp. ]
Store at RT | [solubility ]
DMSO: soluble2mg/mL | [form ]
solid | [pka]
1.60±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
(RS)-PPG is a potent and selective group III mGluR agonist. | [Biological Activity]
A potent and selective group III metabotropic glutamate receptor agonist, with approximately 25-fold preference for hmGlu 8 ; anticonvulsant and neuroprotective in vivo . Also available as part of the Group III mGlu Receptor Tocriset™ . | [IC 50]
hmGluR8a: 0.2 μM (EC50); hmGluR6: 4.7 μM (EC50); hmGluR4a: 5.2 μM (EC50); hmGluR7b: 185 μM (EC50) | [storage]
Store at RT |
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