ChemicalBook--->CAS DataBase List--->1207560-07-3

1207560-07-3

1207560-07-3 Structure

1207560-07-3 Structure
IdentificationBack Directory
[Name]

Bay 43-9006 (D4)
[CAS]

1207560-07-3
[Synonyms]

Bay 43-9006 (D4)
SORAFENIB D4 (BAY 43-9006 D4)
[Molecular Formula]

C21H16ClF3N4O3
[MDL Number]

MFCD21363833
[MOL File]

1207560-07-3.mol
[Molecular Weight]

464.83
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
Hazard InformationBack Directory
[Description]

Sorafenib D4 (Bay 43-9006 D4) is the deuterium labeled Sorafenib. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively.

[Uses]

Sorafenib-d4 is the deuterium labeled Sorafenib. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively.
[storage]

Store at -20°C
[References]

[1]. Wilhelm SM, et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res. 2004 Oct 1;64(19):7099-109.

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