| Identification | Back Directory | [Name]
Bay 43-9006 (D4) | [CAS]
1207560-07-3 | [Synonyms]
Bay 43-9006 (D4)
SORAFENIB D4 (BAY 43-9006 D4) | [Molecular Formula]
C21H16ClF3N4O3 | [MDL Number]
MFCD21363833 | [MOL File]
1207560-07-3.mol | [Molecular Weight]
464.83 |
| Hazard Information | Back Directory | [Description]
Sorafenib D4 (Bay 43-9006 D4) is the deuterium labeled Sorafenib. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively.
| [Uses]
Sorafenib-d4 is the deuterium labeled Sorafenib. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively. | [storage]
Store at -20°C | [References]
[1]. Wilhelm SM, et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res. 2004 Oct 1;64(19):7099-109. |
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