| Identification | Back Directory | [Name]
L-Valine, L-tyrosylglycyl-L-seryl-L-leucyl-L-prolyl-L-glutaminyl-L-lysyl-L-seryl-L-glutaminyl-L-arginyl-L-seryl-L-glutaminyl-L-α-aspartyl-L-α-glutamyl-L-asparaginyl-L-prolyl- | [CAS]
121196-80-3 | [Synonyms]
L-Valine, L-tyrosylglycyl-L-seryl-L-leucyl-L-prolyl-L-glutaminyl-L-lysyl-L-seryl-L-glutaminyl-L-arginyl-L-seryl-L-glutaminyl-L-α-aspartyl-L-α-glutamyl-L-asparaginyl-L-prolyl- | [Molecular Formula]
C81H129N25O30 | [MOL File]
121196-80-3.mol | [Molecular Weight]
1933.04 |
| Chemical Properties | Back Directory | [density ]
1.58±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [color ]
White to off-white | [Sequence]
Tyr-Gly-Ser-Leu-Pro-Gln-Lys-Ser-Gln-Arg-Ser-Gln-Asp-Glu-Asn-Pro-Val |
| Hazard Information | Back Directory | [Uses]
Myelin basic protein, MBP (68-86) is the portion of the 68th to 86th amino acid residues in the MBP protein sequence. Myelin basic protein, MBP (68-86) can act as an autoantigen, triggering the immune system to attack its own myelin. Myelin basic protein, MBP (68-86) is used as one of the immunogens in the experimental autoimmune encephalomyelitis (EAE) animal model to study immune responses associated with multiple sclerosis (MS)[1]. | [References]
[1] Zheng M M, et al. Cross-reactivity between human cytomegalovirus peptide 981-1003 and myelin oligodendroglia glycoprotein peptide 35-55 in experimental autoimmune encephalomyelitis in Lewis rats[J]. Biochemical and biophysical research communications, 2014, 443(3): 1118-1123. DOI:10.1016/j.bbrc.2013.12.122 |
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