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1212650-12-8

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1212650-12-8 Structure

1212650-12-8 Structure
IdentificationBack Directory
[Name]

8-Bromo-9-(beta-D-xylofuranosyl)guanine
[CAS]

1212650-12-8
[Synonyms]

8-Bromo-9-(b-D-xylofuranosyl)guanine
8-Bromo-9-(beta-D-xylofuranosyl)guanine
6H-Purin-6-one, 2-amino-8-bromo-1,9-dihydro-9-β-D-xylofuranosyl-
[Molecular Formula]

C10H12BrN5O5
[MDL Number]

MFCD30748933
[MOL File]

1212650-12-8.mol
[Molecular Weight]

362.14
Chemical PropertiesBack Directory
[Boiling point ]

774.0±70.0 °C(Predicted)
[density ]

2.62±0.1 g/cm3(Predicted)
[pka]

13.00±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

8-Bromo-9-(β-D-xylofuranosyl) guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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Telephone: 021-68689288 15300790979
Website: www.mkbio.com.cn/
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