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121315-93-3

121315-93-3 Structure

121315-93-3 Structure
IdentificationBack Directory
[Name]

1,2-DISTEAROYL-3-DIMETHYLAMMONIUM-PROPANE
[CAS]

121315-93-3
[Synonyms]

18:0 DAP
1,2-DISTEAROYL-3-DIMETHYLAMMONIUM-PROPANE
Octadecanoic acid, 1-[(dimethylamino)methyl]-1,2-ethanediyl ester
[Molecular Formula]

C41H81NO4
[MDL Number]

MFCD00674450
[MOL File]

121315-93-3.mol
[Molecular Weight]

652.09
Chemical PropertiesBack Directory
[Melting point ]

37.5-38.5 °C
[Boiling point ]

671.9±40.0 °C(Predicted)
[density ]

0.905±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C
[form ]

powder
[pka]

8.02±0.28(Predicted)
[InChI]

1S/C41H81NO4/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-40(43)45-38-39(37-42(3)4)46-41(44)36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h39H,5-38H2,1-4H3
[InChIKey]

RVBUSVJSKGVQQS-UHFFFAOYSA-N
[SMILES]

[H]C(CN(C)C)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O
Safety DataBack Directory
[WGK Germany ]

WGK 3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

1,2-distearoyl-3-dimethylammonium-propane (18:0 DAP) might be used to formulate lipid nanoparticles (LNPs) and to test its efficiency of packaging mRNA into an LNP. It might also be used in the preparation of “bubble liposomes” (BLs).
[Biological Activity]

1,2-distearoyl-3-dimethylammonium-propane (18:0 DAP) is a cationic lipid and serves as a pH-sensitive transfection reagent.
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