| Identification | Back Directory | [Name]
N-(3,4-Dimethoxyphenethyl)-3-(4-((3-isopropyl-1-methyl-1H-indol-2-yl)sulfonyl)phenoxy)-N-methylpropan-1-amine oxalate | [CAS]
121346-33-6 | [Synonyms]
| [Molecular Formula]
C34H42N2O9S | [MDL Number]
MFCD00919219 | [MOL File]
121346-33-6.mol | [Molecular Weight]
654.78 |
| Hazard Information | Back Directory | [Uses]
SR 33805 Oxalate is a potent calcium entry blocker. | [in vivo]
SR33805 (20 mg/kg; a single i.p.) improves end-systolic strain and fractional shortening of MI hearts in rats[2].
SR33805 (5 mg/kg/day; p.o. for 38 d) significantly reduces intimal hyperplasia in pigs[3]. | Animal Model: | Male Wistar rats (5 weeks) are subjected to coronary artery ligature[2]. | | Dosage: | 0.2, 2, 20 mg/kg. | | Administration: | A single i.p. injection. | | Result: | Increased significantly both end-systolic strain (ESS) and fractional shortening (FS) by about +38 and +26%, respectively at the dose of 20 mg/kg
Did not affect other contractile parameters.
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| [storage]
Store at RT |
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