| Identification | Back Directory | [Name]
EMD 66684 | [CAS]
1216884-39-7 | [Synonyms]
2-Butyl-3,4-dihydro-N,N-dimethyl-4-oxo-3-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl-4-yl]methyl]-5H-imidazo[4,5-c]pyridine-5-acetamide hydrochloride | [Molecular Formula]
C28H31ClN8O2 | [MDL Number]
MFCD08703087 | [MOL File]
1216884-39-7.mol | [Molecular Weight]
547.06 |
| Hazard Information | Back Directory | [Uses]
EMD 66684 is a useful intermediate. | [in vivo]
EMD 66684 (0.1, 0.3, 1 mg/kg; i.v.; once) results in a long lasting fall in blood pressure[3].
EMD 66684 (0.1 μM; 45 min) decreases the NS-induced overflow of NE and NPY from preparations from SHRs at 10-12 weeks old[4]. | Animal Model: | Conscious furosemide-treated SHR (Spontaneous Hypertension Rat)[3] | | Dosage: | 0.1, 0.3, 1 mg/kg | | Administration: | Intravenous injection; once; as potassium salts to conscious furosemide-treated SHR | | Result: | Showed a long lasting fall in blood pressure, resulted mean arterial pressure (MAP) decreased in a dose-dependent manner.
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| [IC 50]
Angiotensin II Type 1: 0.7 nM (IC50) |
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| Company Name: |
BOC Sciences
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| Tel: |
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| Website: |
https://www.bocsci.com |
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