ChemicalBook--->CAS DataBase List--->1217443-91-8

1217443-91-8

1217443-91-8 Structure

1217443-91-8 Structure
IdentificationBack Directory
[Name]

2-chloro-N6-Cyclopentyladenosine (hydrate)
[CAS]

1217443-91-8
[Synonyms]

2-chloro-N6-Cyclopentyladenosine (hydrate)
[Molecular Formula]

C15H22ClN5O5
[MOL File]

1217443-91-8.mol
[Molecular Weight]

387.82
Chemical PropertiesBack Directory
[solubility ]

DMSO: soluble
Water: soluble
Hazard InformationBack Directory
[Uses]

CCPA hemihydrate is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1][2].
[References]

[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
[2] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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