| Identification | Back Directory | [Name]
3-Acetyl-DON 13C labeled | [CAS]
1217476-81-7 | [Synonyms]
3-Acetyl-DON 13C labeled
3-Acetyldeoxy Nivalenol-13C17
13C17-3-Acetyl-deoxynicalenol
3-Acetyldeoxynivalenol-13C17 solution
3-Acetyldeoxy Nivalenol-13C17 / 13C17-3-Ac-DON | [EINECS(EC#)]
808-632-6 | [Molecular Formula]
13C17H22O7 | [MDL Number]
MFCD11114485 | [MOL File]
1217476-81-7.mol | [Molecular Weight]
355.23 |
| Chemical Properties | Back Directory | [density ]
1.425±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [Fp ]
2 °C | [storage temp. ]
−20°C | [solubility ]
Acetonitrile: Soluble | [form ]
Liquid | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
3-Acetyldeoxynivalenol-13C17 is the 13C labeled 3-Acetyldeoxynivalenol (HY-N6685)[1]. 3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative[2], is a blood-brain barrier (BBB) permeable mycotoxin[3]. | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220. DOI:10.1177/1071100718790255
[2] Kadota T, et al. Comparative study of deoxynivalenol, 3-acetyldeoxynivalenol, and 15-acetyldeoxynivalenolon intestinal transport and IL-8 secretion in the human cell line Caco-2. Toxicol In Vitro. 2013 Sep;27(6):1888-95. DOI:10.1016/j.tiv.2013.06.003
[3] Behrens M, et al. Blood-Brain Barrier Effects of the Fusarium Mycotoxins Deoxynivalenol, 3Acetyldeoxynivalenol, and Moniliformin and Their Transfer to the Brain. PLoS One. 2015 Nov 23;10(11):e0143640. DOI:10.1371/journal.pone.0143640 |
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