| Identification | Back Directory | [Name]
Entereg-d5 | [CAS]
1217616-62-0 | [Synonyms]
Entereg-d5
LY 246736-d5
AlviMopan-d5
ADL 8-2698-d5
Alvimopan-d5 (R&D)
[2H5]-Alvimopan (R&
Avimopan Carboxylic acid metabolite D5
rac-N-[2-[[4-(3-Hydroxyphenyl)-3,4-diMethyl-1-piperidinyl]Methyl]-1-oxo-3-(phenyl-d5)propyl]glycine | [Molecular Formula]
C25H32N2O4 | [MOL File]
1217616-62-0.mol | [Molecular Weight]
424.533 |
| Hazard Information | Back Directory | [Uses]
Labelled Alvimopan. A peripheral μ-opioid receptor antagonist. Gastroprokinetic. | [References]
[1] BERTRAND LE BOURDONNEC . Novel trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines as μ opioid receptor antagonists with improved opioid receptor selectivity profiles[J]. Bioorganic & Medicinal Chemistry Letters, 2008, 18 6: Pages 2006-2012. DOI: 10.1016/j.bmcl.2008.01.106
[2] B GREENWOOD-VAN MEERVELD. Preclinical studies of opioids and opioid antagonists on gastrointestinal function.[J]. Neurogastroenterology and Motility, 2004, 16 Suppl 2: 46-53. DOI: 10.1111/j.1743-3150.2004.00555.x |
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