| Identification | Back Directory | [Name]
(Lys)-Sarafotoxin C | [CAS]
1219444-22-0 | [Synonyms]
(Lys?)-Sarafotoxin C
(Lys4)-Sarafotoxin C
(Lys4)-Sarafotoxin C acetate salt
L-Tryptophan, L-cysteinyl-L-threonyl-L-cysteinyl-L-lysyl-L-α-aspartyl-L-methionyl-L-threonyl-L-α-aspartyl-L-α-glutamyl-L-α-glutamyl-L-cysteinyl-L-leucyl-L-asparaginyl-L-phenylalanyl-L-cysteinyl-L-histidyl-L-glutaminyl-L-α-aspartyl-L-valyl-L-isoleucyl-, cyclic (1→15),(3→11)-bis(disulfide) | [Molecular Formula]
C105H153N27O36S5 | [MOL File]
1219444-22-0.mol | [Molecular Weight]
2529.83 |
| Hazard Information | Back Directory | [Uses]
[Lys4] Sarafotoxin S6c, a sarafotoxin analogue, is a potent and partial agonist of endothelin receptor. [Lys4] Sarafotoxin S6c elicits contraction of pig coronary artery, with an EC50 of 1.5 nM[1]. | [References]
[1] Schoeffter P, et al. Differences between endothelin receptors mediating contraction of guinea-pig aorta and pig coronary artery. Eur J Pharmacol. 1993 Nov 9;249(2):199-206. DOI:10.1016/0014-2999(93)90433-i |
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