| Identification | Back Directory | [Name]
PF-4778574 | [CAS]
1219633-99-4 | [Synonyms]
PF-4778574
PF4778574,PF 4778574
PF-4778574 >=98% (HPLC)
N-[(3R,4S)-3-[4-(5-cyanothiophen-2-yl)phenyl]oxan-4-yl]propane-2-sulfonamide
N-[(3R,4S)-3-[4-(5-Cyano-2-thienyl)phenyl]tetrahydro-2H-pyran-4-yl]-2-propanesulfonamide
N-{(3R,4S)-3-[4-(5-Cyano-2-thienyl)phenyl]tetrahydro-2H-pyran-4-yl}propane-2-sulfonamide
2-Propanesulfonamide, N-[(3R,4S)-3-[4-(5-cyano-2-thienyl)phenyl]tetrahydro-2H-pyran-4-yl]- | [Molecular Formula]
C19H22N2O3S2 | [MDL Number]
MFCD20527887 | [MOL File]
1219633-99-4.mol | [Molecular Weight]
390.52 |
| Chemical Properties | Back Directory | [storage temp. ]
room temp | [solubility ]
DMSO: soluble20mg/mL, clear | [form ]
powder | [color ]
white to beige | [InChI]
1S/C19H22N2O3S2/c1-13(2)26(22,23)21-18-9-10-24-12-17(18)14-3-5-15(6-4-14)19-8-7-16(11-20)25-19/h3-8,13,17-18,21H,9-10,12H2,1-2H3/t17-,18+/m1/s1 | [InChIKey]
FFAGHPLLBXWCSF-MSOLQXFVSA-N | [SMILES]
[S](=O)(=O)(N[C@@H]1[C@H](COCC1)c2ccc(cc2)c3[s]c(cc3)C#N)C(C)C |
| Hazard Information | Back Directory | [Uses]
PF-4778574 may be used as a potentiator of the α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor (AMPAR) in r at cortical neurons. | [Biological Activity]
PF-4778574 is a potent AMPA receptor positive allosteric modulator (PAM) th at has been shown to enhance cognition in animal models. | [storage]
Store at -20°C |
|
| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|