| Chemical Properties | Back Directory | [Boiling point ]
555.4±50.0 °C(Predicted) | [density ]
1.345±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
9.52±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
GNX-865 is a novel mitochondrial permeability transition pore (mtPTP) inhibitor. | [Uses]
GNX-865 is a mitochondrial permeability transition pore (mPTP) inhibitor that protects against ischemia-reperfusion injury in vivo[1]. | [References]
[1] Fancelli D, et al. Cinnamic anilides as new mitochondrial permeability transition pore inhibitors endowed with ischemia-reperfusion injury protective effect in vivo. J Med Chem. 2014 Jun 26;57(12):5333-47. DOI:10.1021/jm500547c |
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