| Identification | Back Directory | [Name]
alldimycin A | [CAS]
122397-46-0 | [Synonyms]
alldimycin A
(7R)-8-Ethyl-7,8,9,10-tetrahydro-1,4,6,7β,8α-pentahydroxy-10α-[[3-(dimethylamino)-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl]oxy]5,12-naphthacenedione
5,12-Naphthacenedione, 8-ethyl-7,8,9,10-tetrahydro-1,4,6,7,8-pentahydroxy-10-[[2,3,6-trideoxy-3-(dimethylamino)-α-L-lyxo-hexopyranosyl]oxy]-, (7R,8R,10S)- (9CI) | [Molecular Formula]
C28H33NO10 | [MOL File]
122397-46-0.mol | [Molecular Weight]
543.57 |
| Hazard Information | Back Directory | [Uses]
Alldimycin A is an anthracycline compound that inhibits RNA and DNA syntheses. Alldimycin A inhibits the growth, DNA and RNA synthesis of murine leukemic L1210, with IC50 values of 0.05 μg/mL, 0.92 μg/mL, and 0.47 μg/mL, respectively[1]. | [References]
[1] Johdo O, et al. Anthracycline metabolites from Streptomyces violaceus A262. V. New anthracycline alldimycin A: a minor component isolated from obelmycin beer. J Antibiot (Tokyo). 1991 Oct;44(10):1160-4. DOI:10.7164/antibiotics.44.1160 |
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