| Identification | Back Directory | [Name]
Butanamide, 2,4-dihydroxy-3,3-dimethyl-N-[3-[(4-methyl-2-oxo-2H-1-benzopyran-7-yl)amino]-3-oxopropyl]-, (2R)- | [CAS]
1224691-12-6 | [Synonyms]
Butanamide, 2,4-dihydroxy-3,3-dimethyl-N-[3-[(4-methyl-2-oxo-2H-1-benzopyran-7-yl)amino]-3-oxopropyl]-, (2R)- | [Molecular Formula]
C19H24N2O6 | [MDL Number]
MFCD31560377 | [MOL File]
1224691-12-6.mol | [Molecular Weight]
376.4 |
| Hazard Information | Back Directory | [Uses]
Pantothenate-AMC is a fluorogenic substrate used for detecting the enzymatic activity of vanin-1, an enzyme involved in the recycling of L-pantothenic acid. Upon enzymatic cleavage by vanin-1, 7-amino-7-methylcoumarin (AMC) is released, and its fluorescence can be used to quantify vanin-1 activity. The excitation/emission maxima of AMC are 340-360 nm and 440-460 nm, respectively[1]. | [References]
[1] Ruan BH, et al. A fluorescent assay suitable for inhibitor screening and vanin tissue quantification. Anal Biochem. 2010 Apr 15;399(2):284-92. DOI:10.1016/j.ab.2009.12.010 |
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