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1226776-54-0

1226776-54-0 Structure

1226776-54-0 Structure
IdentificationBack Directory
[Name]

Ovotransferrin (328-332) trifluoroacetate salt
[CAS]

1226776-54-0
[Synonyms]

Ovotransferrin (328-332)
L-Leucine, L-arginyl-L-valyl-L-prolyl-L-seryl-
Ovotransferrin (328-332) trifluoroacetate salt
[Molecular Formula]

C25H46N8O7
[MDL Number]

None
[MOL File]

1226776-54-0.mol
[Molecular Weight]

570.68
Chemical PropertiesBack Directory
[Sequence]

Arg-Val-Pro-Ser-Leu
Hazard InformationBack Directory
[Uses]

Ovotransferrin (328-332) has a protective activity on the blood pressure by inhibiting the Angiotensin-Converting Enzyme (ACE), with the IC50 of 20 μM. Ovotransferrin (328-332) fragment has an activity against Cholinesterase (ChE), implicating in Alzheimer’s diseases[1][2].
[IC 50]

ACE: 20 μM (IC50)
[References]

[1] Zhipeng Yu, et al. Primary and secondary structure of novel ACE-inhibitory peptides from egg white protein. Food Chem. 2012 Jul 15;133(2):315-22. DOI:10.1016/j.foodchem.2012.01.032
[2] Zhipeng Yu, et al. Anti-Alzheimers activity and molecular mechanism of albumin-derived peptides against AChE and BChE. Food Funct. 2018 Feb 21;9(2):1173-1178. DOI:10.1016/j.foodchem.2012.01.032
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