| Identification | Back Directory | [Name]
Benzenepropanamide, α-[(5-chloro-2-hydroxybenzoyl)amino]-N-(4-chlorophenyl)-, (αR)- | [CAS]
1227476-98-3 | [Synonyms]
MDK6983
MDK-6983
MDK 6983
Compound 6k
Autophagy-IN-3
Autophagy inhibitor 6k
MDK-6983, 10 mM in DMSO
Benzenepropanamide, α-[(5-chloro-2-hydroxybenzoyl)amino]-N-(4-chlorophenyl)-, (αR)- | [Molecular Formula]
C22H18Cl2N2O3 | [MOL File]
1227476-98-3.mol | [Molecular Weight]
429.3 |
| Hazard Information | Back Directory | [Uses]
Autophagy-IN-3 (Compound 6k) is an autophagy inhibitor. Autophagy-IN-3 promotes metabolic stress in the tumor microenvironment and enhances the effects of cytostatics in combined treatments[1]. | [References]
[1] Páchniková G, et al. Substituted 2-hydroxy-N-(arylalkyl)benzamide sensitizes cancer cells to metabolic stress by disrupting actin cytoskeleton and inhibiting autophagic flux. Toxicol In Vitro. 2016 Dec;37:70-78. DOI:10.1016/j.tiv.2016.09.006 |
|
|