| Identification | Back Directory | [Name]
L 657925 | [CAS]
122757-59-9 | [Synonyms]
L 657925
(-)-9-(4-Chlorobenzyl)-6-fluoro-2,3,4,4a,9,9a-hexahydro-1H-carbazole-1-acetic acid
1H-Carbazole-1-acetic acid, 9-[(4-chlorophenyl)methyl]-6-fluoro-2,3,4,4a,9,9a-hexahydro-, (-)- | [Molecular Formula]
C21H21ClFNO2 | [MOL File]
122757-59-9.mol | [Molecular Weight]
373.85 |
| Hazard Information | Back Directory | [Description]
L 657925 is a thromboxane A2 receptor antagonist. | [Uses]
L 657925 is a potent thromboxane A2 (TXA2) antagonist. L 657925 selectively abolishes ONO 11113-evoked transient increment in [Ca22+][1]. | [IC 50]
TXA2 | [References]
[1] Ueda N, et al. Receptor-mediated increase in cytosolic calcium in LLC-PK1 cells by platelet activating factor and thromboxane A2. Kidney Int. 1991 Dec;40(6):1075-81. DOI:10.1038/ki.1991.317 |
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CHEMICAL LAND21
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82- 2 -783 - 8063 |
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www.chemicalland21.com |
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