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1227700-50-6

1227700-50-6 Structure

1227700-50-6 Structure
IdentificationBack Directory
[Name]

MIDA021
[CAS]

1227700-50-6
[Synonyms]

MIDA021
5-Bromopyridine-2-boronic acid MIDA ester
5-Bromopyridine-2-boronic acid MIDA ester 95% (HPLC)
Boron, (5-bromo-2-pyridinyl)[N-[(carboxy-κO)methyl]-N-methylglycinato(2-)-κN,κO]-, (T-4)-
8-(5-Bromopyridin-2-yl)-4-methyldihydro-4λ4,8λ4-[1,3,2]oxazaborolo[2,3-b][1,3,2]oxazaborole-2,6(3H,5H)-dione
[Molecular Formula]

C10H10BBrN2O4
[MDL Number]

MFCD23097053
[MOL File]

1227700-50-6.mol
[Molecular Weight]

312.91
Chemical PropertiesBack Directory
[Melting point ]

220-225°C (decomposition)
[form ]

solid
[InChI]

1S/C10H10BBrN2O4/c1-14-5-9(15)17-11(18-10(16)6-14)8-3-2-7(12)4-13-8/h2-4H,5-6H2,1H3
[InChIKey]

RSJASKKCIPMBEE-UHFFFAOYSA-N
[SMILES]

BrC1=CC=C(B2OC(CN(C)CC(O2)=O)=O)N=C1
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26
[WGK Germany ]

3
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazard InformationBack Directory
[Uses]

The 2-substituted pyridinyl boronic acid has classically been a challenging motif to install, due to instability of the boronic acid. The MIDA Boronate now enables a highly effecient means of installing the 2-pyridyl motif through Suzuki-Miyuara coupling.

A General Solution for the 2-Pyridyl Problem
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