ChemicalBook--->CAS DataBase List--->1227923-29-6

1227923-29-6

1227923-29-6 Structure

1227923-29-6 Structure
IdentificationBack Directory
[Name]

3-[(1S,2S)-2-Hydroxycyclohexyl]-6-[(6-methyl-3-pyridinyl)methyl]benzo[h]quinazolin-4(3H)-one
[CAS]

1227923-29-6
[Synonyms]

MK7622
MK-7622
MK 7622
M1 receptor
M1 receptor modulator
MK7622; MK 7622; MK-7622.
MK-7622;MK 7622;M1 RECEPTOR MODULATOR
3-[(1S,2S)-2-hydroxycyclohexyl]-6-[(6-methylpyridin-3-yl)methyl]benzo[h]quinazolin-4-one
3-[(1S,2S)-2-Hydroxycyclohexyl]-6-[(6-methyl-3-pyridinyl)methyl]benzo[h]quinazolin-4(3H)-one
3-((1S,2S)-2-hydroxycyclohexyl)-6-((6-Methylpyridin-3-yl)Methyl)benzo[h]quinazolin-4(3H)-one
Benzo[h]quinazolin-4(3H)-one, 3-[(1S,2S)-2-hydroxycyclohexyl]-6-[(6-methyl-3-pyridinyl)methyl]-
[Molecular Formula]

C25H25N3O2
[MDL Number]

MFCD22419022
[MOL File]

1227923-29-6.mol
[Molecular Weight]

399.48
Chemical PropertiesBack Directory
[density ]

1.30
[storage temp. ]

Store at -20°C
[solubility ]

DMSO:100.0(Max Conc. mg/mL);250.33(Max Conc. mM)
[form ]

A solid
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

MK-7622 (M1 receptor modulator) is a muscarinic M1 receptor positive allosteric modulator[1][2].
[storage]

Store at -20°C
[References]

[1] Kuduk Scott D, et al. Dihydrobenzoquinazolinone M1 receptor positive allosteric modulators. From PCT Int. Appl. (2012), WO 2012047702 A1 20120412.
[2] Kuduk Scott D, et al. Benzoquinazolinone derivatives as M1 receptor positive allosteric modulators and their preparation, pharmaceutical compositions and use in the treatment of diseases. From PCT Int. Appl. (2010), WO 2010059773 A1 20100527.
Spectrum DetailBack Directory
[Spectrum Detail]

3-[(1S,2S)-2-Hydroxycyclohexyl]-6-[(6-methyl-3-pyridinyl)methyl]benzo[h]quinazolin-4(3H)-one(1227923-29-6)1HNMR
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