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1228078-57-6

1228078-57-6 Structure

1228078-57-6 Structure
IdentificationBack Directory
[Name]

Sodium (R)-3-hydroxy-2-methylpropionate
[CAS]

1228078-57-6
[Synonyms]

R-HIBA
R-β-HIBA-Na
Sodium (R)-β-hydroxyisobutyrate
Sodium (R)-3-hydroxy-2-methylpropionate
(R)-β-Hydroxyisobutyric acid sodium salt
Sodium (R)-beta-hydroxyisobutyrate >=96.0%
(R)-3-Hydroxy-2-methylpropionic acid sodium salt
[Molecular Formula]

C4H9NaO3
[MDL Number]

MFCD17215934
[MOL File]

1228078-57-6.mol
[Molecular Weight]

128.1
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[InChI]

1S/C4H8O3.Na/c1-3(2-5)4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1/t3-;/m1./s1
[InChIKey]

RBJZIQZDAZLXEK-AENDTGMFSA-M
[SMILES]

[Na+].C[C@H](CO)C([O-])=O
Safety DataBack Directory
[WGK Germany ]

3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

3-Hydroxyisobutyrate (HIBA) may be used to study the distribution, characterization and kinetics of enzymes involved in branched chain amino acid metabolism such as 3-hydroxyisobutyrate dehydrogenase (EC: 1.1.1.31) and 3-hydroxyisobutyryl-CoA hydrolase (EC: 3.1.2.4). (R)-β-hydroxyisobutyrate may be used in stereospecific studies.
[Biological Activity]

Increased urinary concentrations of 3-hydroxyisobutyric acid are a biochemical hallmark of metabolic disease 3-hydroxyisobutyric aciduria.
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