| Identification | Back Directory | [Name]
2-Thiazolidinone, 4-(18-hydroxy-4,12-dimethyl-14-oxo-8,15,19-trioxatricyclo[14.3.1.07,9]eicosa-5,12-dien-18-yl)-, [1R-[1R*,4S*,5Z,7S*,9S*,12Z,16R*,18S*(R*)]]- (9CI) | [CAS]
122876-48-6 | [Synonyms]
Latrunculins A
2-Thiazolidinone, 4-(18-hydroxy-4,12-dimethyl-14-oxo-8,15,19-trioxatricyclo[14.3.1.07,9]eicosa-5,12-dien-18-yl)-, [1R-[1R*,4S*,5Z,7S*,9S*,12Z,16R*,18S*(R*)]]- (9CI) | [Molecular Formula]
C22H31NO6S | [MOL File]
122876-48-6.mol | [Molecular Weight]
437.55 |
| Hazard Information | Back Directory | [Description]
Latrunculins A is a novel marine toxin that disrupt microfilament organization in cultured cells. | [Uses]
6,7-Epoxy-latrunculin A can be isolated from the Red Sea sponge Negombata magnifica and is initially identified as an inhibitor of actin polymerization by its morphological effects[1]. | [References]
[1] James D. White, et al. Total synthesis of (+)-latrunculin A, an ichthyotoxic metabolite of the sponge Latrunculia magnifica and its C-15 epimer. The Journal of Organic Chemistry. 1992. |
|
|