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1228927-36-3

1228927-36-3 Structure

1228927-36-3 Structure
IdentificationBack Directory
[Name]

L-Glutamic acid, N-[[[(1S)-1-[(1,1-dimethylethoxy)carbonyl]-4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl]amino]carbonyl]-, 1,5-bis(1,1-dimethylethyl) ester
[CAS]

1228927-36-3
[Synonyms]

L-Glutamic acid, N-[[[(1S)-1-[(1,1-dimethylethoxy)carbonyl]-4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl]amino]carbonyl]-, 1,5-bis(1,1-dimethylethyl) ester
[Molecular Formula]

C27H43N3O11
[MOL File]

1228927-36-3.mol
[Molecular Weight]

585.64
Chemical PropertiesBack Directory
[density ]

1.22±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

11.97±0.46(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Glu-urea-Glu-NHS ester (compound 21) is an activated N-hydroxysuccinamide (NHS) ester of Glu-urea-Glu which can be used as a pharmacophore for linking with prostate specific membrane antigen (PSMA) inhibitors[1].
[References]

[1] Lu G, et al. Synthesis and SAR of ??mTc/Re-labeled small molecule prostate specific membrane antigen inhibitors with novel polar chelates. Bioorg Med Chem Lett. 2013 Mar 1;23(5):1557-63. DOI:10.1016/j.bmcl.2012.09.014
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