| Identification | Back Directory | [Name]
1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine | [CAS]
123027-56-5 | [Synonyms]
1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine
1-[(2-hydroxyethoxy)methyl]-6-(phenylsulfanyl)thymine
1-(2-hydroxyethoxymethyl)-5-methyl-6-phenylsulfanylpyrimidine-2,4-dione
1-[(2-hydroxyethoxy)methyl]-5-methyl-6-(phenylthio)2,4(1H, 3H)-pyrimidinedione
2,4(1H,3H)-Pyrimidinedione, 1-[(2-hydroxyethoxy)methyl]-5-methyl-6-(phenylthio)- | [Molecular Formula]
C14H16N2O4S | [MDL Number]
MFCD00887737 | [MOL File]
123027-56-5.mol | [Molecular Weight]
308.35 |
| Hazard Information | Back Directory | [Uses]
HEPT is a potent and selective anti-HIV-1 agent[1]. | [Definition]
ChEBI: A pyrimidone that is thymine which is substituted at positions 1 and 6 by a (2-hydroxyethoxy)methyl group and a phenylsulfanyl group, respectively. | [References]
[1] Tanaka H, et al. A new class of HIV-1-specific 6-substituted acyclouridine derivatives: synthesis and anti-HIV-1 activity of 5- or 6-substituted analogues of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT). J Med Chem. 1991 Jan;34(1):349-57. DOI:10.1021/jm00105a055 |
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