ChemicalBook--->CAS DataBase List--->1231898-25-1

1231898-25-1

1231898-25-1 Structure

1231898-25-1 Structure
IdentificationBack Directory
[Name]

BIOTIN-TAT (47-57)
[CAS]

1231898-25-1
[Synonyms]

BIOTIN-YGRKKRRQRRR
BIOTIN-TAT (47-57)
BIOTIN-TYR-GLY-ARG-LYS-LYS-ARG-ARG-GLN-ARG-ARG-ARG-OH
[Molecular Formula]

C74H132N34O16S
[MDL Number]

MFCD08459547
[MOL File]

1231898-25-1.mol
[Molecular Weight]

1786.12
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Biotin-TAT (47-57), a biotin tagged TAT, is a transactivator of transcription. Biotin-TAT (47-57) is one of the most widely used protein transduction domains (PTDs) into different primary cells is ATP- and temperature-dependent, indicating the involvement of endocytosis[1][2].
[References]

[1] Chen Sun, et al. Intracellular tracking of single native molecules with electroporation-delivered quantum dots. Anal Chem. 2014 Nov 18;86(22):11403-9. DOI:10.1021/ac503363m
[2] Jean Philippe Richard, et al. Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors. J Biol Chem. 2005 Apr 15;280(15):15300-6. DOI:10.1074/jbc.M401604200
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