| Identification | Back Directory | [Name]
5-hydroxy-2-(1'-hydroxyethyl)naphtho[2,3-b]furan-4,9-dione | [CAS]
123297-90-5 | [Synonyms]
STAT3-IN-14
5-hydroxy-2-(1'-hydroxyethyl)naphtho[2,3-b]furan-4,9-dione | [Molecular Formula]
C14H10O5 | [MOL File]
123297-90-5.mol | [Molecular Weight]
258.226 |
| Hazard Information | Back Directory | [Uses]
STAT3-IN-14 (Compound 1) is a STAT3 inhibitor and has STAT3 phosphorylation inhibitory activity. STAT3-IN-14 (Compound 1) can directly bind to the hinge region of STAT3[1]. | [References]
[1] Teruyuki Tahara, et al. STAT3 inhibitory activity of naphthoquinones isolated from Tabebuia avellanedae. Bioorg Med Chem. 2020 Mar 15;28(6):115347. DOI:10.1016/j.bmc.2020.115347 |
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