| Hazard Information | Back Directory | [Description]
TASP0376377 is a potent CRTH2 Antagonist. | [Uses]
TASP0376377 is a potent and selective CRTH2 antagonist (IC50: 13 nM). TASP0376377 has binding affinity for CRTH2 (IC50: 19 nM)[1]. | [References]
[1] Nishikawa-Shimono R, et al. Isoquinoline derivatives as potent CRTH2 antagonists: design, synthesis and SAR. Bioorg Med Chem. 2013 Dec 15;21(24):7674-85. DOI:10.1016/j.bmc.2013.10.025 |
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