| Identification | Back Directory | [Name]
17-keto-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid | [CAS]
1233715-28-0 | [Synonyms]
QCEBQMMZCFADMF-VIIQGJSXSA-N
17-oxo-(4Z),(7Z),(10Z),(13Z),(15E),(19Z)-Docosahexaenoic Acid
17-keto-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid
4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-17-keto-Docosahexaenoic acid
4,7,10,13,15,19-Docosahexaenoic acid, 17-oxo-, (4Z,7Z,10Z,13Z,15E,19Z)- | [Molecular Formula]
C22H30O3 | [MOL File]
1233715-28-0.mol | [Molecular Weight]
342.47 |
| Chemical Properties | Back Directory | [Boiling point ]
500.4±50.0 °C(Predicted) | [density ]
0.992±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 15 mg/ml; DMSO: 10 mg/ml; Ethanol: 20 mg/ml | [pka]
4.58±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
17-Oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-docosahexaenoic acid (17-Oxo-DHA) is a metabolite of lipoxygenase-mediated oxidation of DHA. 17-Oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-docosahexaenoic acid is a PPARγ agonist and activates a Nrf2 dependent antioxidant reaction[1]. | [storage]
Store at -20°C | [References]
[1] Groeger AL, et al. Cyclooxygenase-2 generates anti-inflammatory mediators from omega-3 fatty acids. Nat Chem Biol. 2010 Jun;6(6):433-41. DOI:10.1038/nchembio.367 |
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