| Identification | Back Directory | [Name]
Δ2-Cefuroxime Axetil | [CAS]
123458-61-7 | [Synonyms]
Δ2-Cefuroxime Axetil
Cefuroxim Impurity 34
Cefuroxim Impurity 10
Delta2-Cefuroxime axetil
Cefuroxim axetil impurity A
Cefuroxime Axetil EP Impurity A
Cefuroxime Axetil Impurity A (EP)
Cefuroxime Axetil Impurities (EP)
(6R,7R)-1-acetoxyethyl 3-((carbamoyloxy)methyl)
Cefuroxime Axetil Impurity A (EP)（Δ3-Cefuroxime Axetil）
Cefuroxime Impurity 34(Cefuroxime Axetil EP Impurity A)
Δ2-Cefuroxime Axetil
(Cefuroxime Axetil Delta-3 Isomer)
delta2-Cefuroxime Axetil (Cefuroxime Axetil Delta-3 Isomer)
1-acetoxyethyl (6R,7R)-3-((carbamoyloxy)methyl)-7-((Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylate
1-acetyloxyethyl (6R,7R)-3-(carbamoyloxymethyl)-7-[[(2Z)-2-(furan-2-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylate
[6R-[6α, 7β(Z)]]-3-[[(Aminocarbonyl)oxy]methyl]-7-[[2-furanyl(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid 1-(acetyloxy)ethyl ester
(6R,7R)-1-Acetoxyethyl 3-((carbamoyloxy)methyl)-7-((Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylate (Cefuroxime Impurity)
(6R,7R)-3-[[(AMinocarbonyl)oxy]Methyl]-7-[[(2Z)-2-(2-furanyl)-2-(MethoxyiMino)acetyl]aMino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic Acid 1-(Acetyloxy)ethyl Ester
5-Thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-, 1-(acetyloxy)ethyl ester, (6R,7R)- | [Molecular Formula]
C20H22N4O10S | [MDL Number]
MFCD00864991 | [MOL File]
123458-61-7.mol | [Molecular Weight]
510.474 |
| Chemical Properties | Back Directory | [Melting point ]
64-71°C | [density ]
1.61±0.1 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
neat | [pka]
8.33±0.60(Predicted) | [color ]
White to Pale Yellow | [Stability:]
Hygroscopic | [Major Application]
pharmaceutical (small molecule) | [InChIKey]
AQVGUOHUYICCIZ-WDVFJNCVSA-N | [SMILES]
S1[C@H]2N(C(C(=C1)COC(=O)N)C(=O)OC(OC(=O)C)C)C(=O)[C@H]2NC(=O)\C(=N/OC)\c3[o]ccc3 |
| Hazard Information | Back Directory | [Uses]
It is an oral prodrug of Cefuroxime (C248060), an injectable second generation cephalosporin with an excellent antibacterial activity. This ester is applied in therapy as a mixture of the R and S diastereoisomers. | [Synthesis]
The ethyl acetate solution of δ2-cefuroxime was concentrated to 30% under vacuum -0.99 MPa to obtain δ2-cefuroxime concentrate.
To 25 ml of isopropyl ether or petroleum ether, add 0.2 g of δ2- cefuroxime crystalline seed and stir rapidly to obtain cefuro |
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PI & PI BIOTECH INC.
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+86-13602409664 +86-17788709170 |
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www.paypaytech.com/ |
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