| Identification | Back Directory | [Name]
4-(4-(prop-2-ynyloxy)benzoyl)benzoic acid | [CAS]
1236196-77-2 | [Synonyms]
propargyloxybenzophenone carboxylic acid
4-(4-(prop-2-ynyloxy)benzoyl)benzoic acid
4-[4-(2-Propyn-1-yloxy)benzoyl]benzoic Acid
4-(4-(Prop-2-yn-1-yloxy)benzoyl)benzoic acid
Benzoic acid, 4-[4-(2-propyn-1-yloxy)benzoyl]-
4-(4-(Prop-2-yn-1-yloxy)benzoyl)benzoic acid >=95% | [Molecular Formula]
C17H12O4 | [MOL File]
1236196-77-2.mol | [Molecular Weight]
280.27 |
| Chemical Properties | Back Directory | [Melting point ]
>200°C (dec.) | [Boiling point ]
498.5±40.0 °C(Predicted) | [density ]
1.269±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
Acetone (Slightly), Methanol (Slightly) | [form ]
solid | [pka]
3.73±0.10(Predicted) | [color ]
Pale Beige to Light Beige | [InChI]
1S/C17H12O4/c1-2-11-21-15-9-7-13(8-10-15)16(18)12-3-5-14(6-4-12)17(19)20/h1,3-10H,11H2,(H,19,20) | [InChIKey]
URDMKFAPEKSQDV-UHFFFAOYSA-N | [SMILES]
O=C(C1=CC=C(OCC#C)C=C1)C2=CC=C(C(O)=O)C=C2 |
| Hazard Information | Back Directory | [Uses]
4-(4-(Prop-2-yn-1-yloxy)benzoyl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments. | [Uses]
4-[4-(2-Propyn-1-yloxy)benzoyl]benzoic Acid, is a benzophenone residue used for Protein Photolabeling. It can also be used for the synthesis of new Thiodigalactoside-Based chemical probes to label galectin-3. | [reaction suitability]
reaction type: click chemistry
reagent type: cross-linking reagent |
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